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ITOKI CORPORATION (Head Office: Chuo-ku, Tokyo; President: Tadashi Sawada), a group company of Dalton Corporation (Head Office: Chuo-ku, Tokyo; President: Koji Minato), will exhibit at Interphex Japan 2026, a pharmaceutical and cosmetics research and manufacturing exhibition to be held from May 20 (Wed) to 22 (Fri), 2026, at Makuhari Messe, Chiba. The exhibition will be held at Makuhari Messe, Chiba, Japan, from May 20 (Wed) to 22 (Fri), 2026.

Dalton has booths in two zones. In the sterilization and cleanroom zone, visitors can experience solutions for creating sterile, clean, and containment environments, including new isolators designed for research and development environments of sterile pharmaceuticals. In the raw material processing zone, visitors can experience containment grinders that can handle highly potent pharmaceuticals as standalone equipment, as well as solutions that enable continuous production of solid dosage forms.

Based on the concept of "Dalton's proposed 'clean' environment construction," we will introduce isolators that realize the sterile environment required in the fields of highly potent pharmaceuticals, gene therapy, and regenerative medicine with energy saving, space saving, and high operability, as well as products that enable DX in pharmaceutical research, development, and manufacturing, and solutions that enable real-time measurement of VOCs in the air. Many other products will also be on display, allowing you to see the elements of creating a "clean" environment.

<Main exhibited products>
• Sterile isolator Sterigion®​
By incorporating our proprietary decontamination system into the isolator, we have solved challenges such as shortening decontamination time, achieving a compact design, and reducing the risk of failure of precision equipment, all in one unit.
We have achieved approximately 50% reduction in hydrogen peroxide consumption used for decontamination and approximately 40% reduction in total decontamination time (both compared to our previous models). In addition, by incorporating our proprietary SurePack® filter system, which reduces the contaminated area and ensures worker safety, and by clearly defining the decontamination area within the isolator, we have made the entire device 30% more compact than our previous models.
Furthermore, during decontamination, the system maintains an optimal internal environment for decontamination while simultaneously controlling the environment in real time to prevent excessive condensation, thereby reducing the risk of malfunctions in precision equipment.
In this system, the isolator and decontamination system can be controlled and monitored using a single touch panel, achieving intuitive operation and manageability.

• Automated cell culture system centered around Pure Q-be®
This system automates cell culture in regenerative medicine and cell therapy, supporting improved reproducibility and homogeneity, and reducing reliance on human labor.
The "Pure Q-be®" isolation clean bench, capable of creating an ISO 5 (Class 100) environment, is equipped with a TX2-40 pharmaceutical robot (manufactured by Stäubli). This system will be used to demonstrate the automated dispensing of liquid culture media and cell suspensions.

Air Tox Solutions - Real-time monitoring system for trace VOCs in the atmosphere
This is a device from TOFWERK, a Swiss company, that enables real-time monitoring of volatile organic compounds (VOCs) in the atmosphere. By accurately measuring PRTR-targeted substances and VOCs in laboratories and manufacturing plants, it contributes to efforts to prevent environmental pollution. Conventional methods, mainly using chromatography-mass spectrometers, required time for quantitative analysis through offline cumulative measurement. However, Air Tox Solutions allows for real-time analysis of which substances are present and in what quantities. Measurements are possible at the pptv level, so you can verify the results with extremely high analytical accuracy.

Dalton's CS Equipment Division will be exhibiting in the sterilization and cleanroom zone.

We will be exhibiting a new type of pulverizer that combines containment performance and workability for highly pharmacologically active drugs, as well as a micro-fluidized bed, a tumbler mixer, and a real-time mixing degree measurement system using NIR. You can consult with our expert staff regarding various challenges such as production efficiency, sophistication, and cost reduction.

<Main exhibited products>
Containment crusher
This new pulverizer combines containment performance and ease of use, making it suitable for highly potent drugs. In a test* evaluating how well the device alone can prevent powder leakage, the results showed that the powder concentration was 0.1 μg/m³ or less at all measurement points. This demonstrates that the device can suppress powder scattering to an extremely high level under the test conditions, making it suitable for use in manufacturing environments where suppressing powder scattering is required.
This single device can handle different particle sizes and raw material characteristics, whether for pin-type or hammer-type processing.
Furthermore, we can flexibly accommodate various requests regarding the input and collection of raw materials. Cleaning can be performed by wet-down to eliminate dust generation before parts replacement can be carried out.

*1 kg of mannitol was placed in a hopper and measured at each stage of the process, from crushing to washing and disassembly, using a method compliant with SMEPAC (APCPPE).

• Granulation and coating equipment: Micro-fluidized bed
Experiments can be conducted starting with 3g of granulated material and 0.3g of coated material. This shortens experimental time and is effective for multi-sample screening and ensuring sufficient sample size (n).
We offer a wide variety of parts, such as spray nozzles and bag filters, so you can select the right one for your specific needs.

• Continuous granulation system DOME-EX system
This system enables continuous production of solid dosage forms.
We process each batch stage—precise mixing, kneading, granulation, and drying—in a single step. We offer PAT tools that provide excellent content uniformity, maintain quality over long periods, and are ideal for continuous production. We also have smoothing mixers necessary before tableting.

In the raw material processing zone, Dalton's powder machinery division will be exhibiting.